“Family Guy” has never shied away from embedding a multitude of pop culture references into each episode, and the fourth episode of the first season, “Mind Over Murder,” continues this tradition. This episode, which originally aired on April 25, 1999, is filled with nods to various facets of popular culture, from movies and television shows to historical figures and events. Here, we delve into some of the most notable references.

1. The Patty Duke Show

In a humorous nod to classic television, Stewie’s experiment with a mind control device mirrors the split-screen technique used in “The Patty Duke Show.” This sitcom, which aired from 1963 to 1966, is known for Patty Duke playing identical cousins with contrasting personalities. In “Mind Over Murder,” Stewie uses the device to bring his teddy bear Rupert to life, a scenario that humorously pays homage to the dual roles of Patty Duke.

2. The Time Machine by H.G. Wells

Stewie’s construction of a time machine in the basement is a direct reference to H.G. Wells’ science fiction novel, “The Time Machine.” This literary reference underscores Stewie’s advanced intellect and his ambitions that far exceed his infantile constraints.

3. “Cheers” Theme Song

The episode cleverly incorporates the theme song from “Cheers,” a popular American sitcom that ran from 1982 to 1993. This occurs during a scene where Peter decides to build a bar in the basement, evoking the camaraderie and atmosphere of the show’s iconic bar setting.

4. Rodney Dangerfield

Peter’s lack of respect from his family and friends in this episode echoes the comedy of Rodney Dangerfield, known for his catchphrase, “I get no respect!” This reference is highlighted through Peter’s continuous efforts to win over his wife Lois and gain admiration from his peers.

5. “The More You Know” Public Service Announcements

A scene in the episode parodies “The More You Know” public service announcements that aired on NBC starting in the late 1980s. The use of a shooting star graphic and the moral lessons tied to these segments are humorously applied to Peter’s realization about respecting his wife’s wishes.

6. Stephen Hawking

In a more subtle reference, Stewie’s intelligence and physical limitations (being an infant) are jokingly compared to those of renowned physicist Stephen Hawking. This comparison is made through Stewie’s dialogue and his ambitious scientific endeavors, despite being in a baby’s body.

7. Musical References: Frank Sinatra and Bobby Darin

The episode features music that evokes the era of Frank Sinatra and Bobby Darin, particularly during scenes in Peter’s basement bar. This choice of music sets the atmosphere, linking Peter’s endeavor to create a social gathering spot to the classic entertainment venues of the past.