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Diabetes ‘Wonder Drug’ Metformin Fails to Deliver in Cancer Treatment - In 2005, an observational study of almost 12,000 people with diabetes hinted that the type 2 diabetes drug metformin might also work against cancer, suggesting a 23% lower rate of cancer among those who had taken it. Since then, thousands of papers have explored this idea, but no gold-standard clinical evidence has emerged to support the theories. Recent trials for two types of cancer have reported no benefits from metformin. Early observational studies might have exaggerated metformin’s potential because of ‘immortal time bias,’ a phenomenon where individuals who died from cancer were not able to try metformin, creating an illusion of a survival benefit. Despite initial excitement, metformin has not lived up to its promise as a cancer treatment. Researchers have conducted numerous studies on lab cells, animals, and humans, but the results have been inconsistent. Some studies suggested that metformin could slow the growth of various cancer cells and enhance their sensitivity to chemotherapy drugs, but these findings haven't translated into successful clinical trials. The lack of conclusive evidence has led many experts to advise against using metformin as a cancer treatment. For instance, Pamela Goodwin, an epidemiologist and medical oncologist, often receives inquiries from patients about whether they should take metformin for cancer treatment, to which she advises against it due to the lack of definitive proof. While metformin remains a leading treatment for type 2 diabetes, its potential as a cancer therapy has not materialized. More research is required to understand the mechanisms by which metformin might affect cancer cells and determine whether it could be repurposed for cancer prevention or treatment. In conclusion, metformin’s journey from a diabetes drug to a potential cancer treatment has been one of hope and disappointment. Although initial studies were promising, the lack of clinical evidence has dashed the hopes of researchers and patients alike. The search for effective cancer treatments continues, with metformin’s story serving as a reminder of the complexities and challenges of drug repurposing.
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May 17, 2025

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One Of The Most Obvious Credibility Killers Is Lying

The Credibility Killer: The Destructive Impact of Lies Introduction Credibility is a precious and delicate quality that every individual and…
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Creativity is often associated with originality, innovation, and artistic expression, but defining what makes something truly “creative” is more complex. Creativity is not just about producing something new—it involves meaningful transformation, problem-solving, and a unique perspective that challenges conventional thinking. Whether in art, science, business, or daily life, creativity is recognized by certain key characteristics.

1. Originality: The Foundation of Creativity

One of the primary markers of creativity is originality. A creative work, idea, or solution must be distinct from what already exists. However, originality does not always mean complete novelty—it often involves combining existing elements in a fresh way.

  • A musician blending genres to create a new sound.
  • An inventor adapting technology to solve an old problem.
  • A writer using a classic story structure with an unexpected twist.

If something lacks uniqueness and simply replicates what already exists, it is not truly creative—it is imitation.

2. Problem-Solving: Creativity as a Functional Tool

Creativity is not limited to artistic expression. Some of the most impactful creative work comes from solving problems in unexpected ways. This is evident in fields like science, engineering, and business.

  • A scientist developing a new theory to explain a natural phenomenon.
  • An entrepreneur designing an innovative product that meets an unmet need.
  • A teacher creating an unconventional method to engage students.

Creative problem-solving involves thinking beyond the obvious and finding solutions where others see limitations.

3. Expression of Emotion and Meaning

Creativity often carries an emotional or intellectual depth. It resonates with people, sparks conversation, or provokes thought. This is why great art, literature, and music feel impactful—they go beyond technical skill and connect with human emotions or deeper ideas.

  • A painting that captures a feeling in a way words cannot.
  • A film that explores a universal human struggle.
  • A speech that inspires people to think differently.

Creativity is not just about making something new—it is about making something that matters.

4. Risk-Taking: Challenging the Status Quo

Creativity involves stepping outside comfort zones. True creative work often challenges norms and takes risks, whether through unconventional thinking, breaking traditional rules, or presenting ideas that may not be immediately accepted.

  • A filmmaker using an experimental narrative style.
  • A business leader pursuing an unconventional strategy.
  • A poet redefining the structure of language.

Risk-taking is crucial because it opens the door for breakthroughs. Many creative pioneers were initially met with skepticism before their ideas became widely recognized.

5. Adaptability: Creativity Evolves Over Time

Creativity is not static—it evolves in response to new challenges, cultural shifts, and personal growth. What is considered creative today may not be seen the same way in the future. Adaptability is what allows creativity to remain relevant and impactful.

  • A photographer embracing digital art in an era of AI.
  • A chef blending traditional recipes with modern techniques.
  • A scientist modifying theories based on new discoveries.

Creativity is fluid, and the most creative individuals and works often continue to evolve.

Conclusion

Something is defined as creative when it is original, problem-solving, emotionally expressive, risk-taking, and adaptable. Creativity is not confined to art—it is found in every field where people push boundaries, challenge conventions, and offer fresh perspectives. It is not just about making something new—it is about making something meaningful that has the power to inspire, change, or solve problems in ways others might not have imagined.


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